产品货号：
Z26804
中文名称：
SIGIRR抗体
英文名称：
Anti-SIGIRR Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SIGIRR Antibody |
| 指标别名 | SIGIRR;TIR8;Toll/interleukin 1 receptor 8 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ELISA |
| 基因名称 | SIGIRR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 计算分子量 | 46KD |
| 成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
| 纯化方式 | SIGIR antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | SIGIRR is a member of the Toll-like receptor-interleukin 1 receptor superfamily.Members of this family are defined by the presence of an intracellular Toll-IL-1R (TIR) domain.The Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.SIGIRR was originally identified through database analysis and was shown to have only one Ig domain as opposed to the normal three Ig folds seen in the TIR family.Similar to ST2,another TIR family member,it has been shown to negatively regulate IL-1 receptor and Toll-like receptor signaling.However,SIGIRR inhibits TLR-IL-1R signaling by dimerizing with TLR4,TLR5,TLR9,and IL-1R.It also associates with the down-stream TLR signaling proteins IRAK and TRAF6 in an IL-1-dependent fashion. |
| Uniprot ID | Q6IA17 |
| 基因名全称 | Single Ig IL-1-related receptor |
| 蛋白名全称 | Single Ig IL-1-related receptor |
| 推荐稀释比 | WB 1:500～2000 ELISA 1:5000～20000 |
相关搜索：SIGIRR抗体，SIGIRR多抗，Anti-SIGIRR Antibody